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Analytical Characterization of Biotherapeutics



Edited by Jennie R. Lill and Wendy Sandoval




Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc.
South San Francisco, CA, USA






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“To Joe and Charlie, thank you for your wonderful smiles and boundless energy”

Jennie R. Lill


“To my daughters, Nicolina and Olivia, who are my daily inspiration”

Wendy Sandoval

List of Contributors

Corey E. Bakalarski
Departments of Microchemistry, Proteomics & Lipidomics and Bioinformatics & Computational Biology
Genentech Inc.
South San Francisco, CA, USA

Anne Baldwin
Departments of Biomolecular Engineering and Proteomics & Biological Resources
Genentech Inc.
South San Francisco, CA, USA

Karen Billeci
Department of Proteomics & Biological Resources
Genentech Inc.
South San Francisco, CA, USA

John B. Briggs
Department of Protein Analytical Chemistry
Genentech Inc.
South San Francisco, CA, USA

Natalie Castellana
Digital Proteomics LLC
La Jolla
and
Mapp Biopharmaceutical, Inc.
San Diego, CA, USA

Paola Di Lello
Department of Structural Biology
Genentech Inc.
South San Francisco, CA, USA

Diego Ellerman
Department of Protein Chemistry and Structural Biology
Genentech Inc.
South San Francisco, CA, USA

Adrian Guthals
Digital Proteomics LLC
La Jolla
andMapp Biopharmaceutical, Inc.
San Diego, CA, USA

Robert F. Kelley
Drug Delivery Department
Genentech Inc.
South San Francisco, CA, USA

Denise Krawitz
Department of Analytical Operations
Genentech Inc.
South San Francisco, CA, USA

Jennie R. Lill
Department of Microchemistry, Proteomics & Lipidomics
Genentech Inc.
South San Francisco, CA, USA

Yichin Liu
Department of Biochemical and Cellular Pharmacology
Genentech Inc.
South San Francisco, CA, USA

T. Noelle Lombana
Department of Antibody Engineering
Genentech Research and Early Development
South San Francisco, CA, USA

Patrick Lupardus
Department of Structural Biology
Genentech Inc.
South San Francisco, CA, USA

Till Maurer
Department of Protein Chemistry and Structural Biology
Genentech Inc.
South San Francisco, CA, USA

Christopher M. Overall
Center for Blood Research
University of British Columbia
Vancouver, British Columbia, Canada

Wilson Phung
Department of Microchemistry, Proteomics & Lipidomics
Genentech Inc.
South San Francisco, CA, USA

Jason C. Rouse
Department of Analytical Research and Development
Pfizer
Cambridge, MA, USA

Wendy Sandoval
Department of Microchemistry, Proteomics & Lipidomics
Genentech Inc.
South San Francisco, CA, USA

Justin M. Scheer
Antibody Engineering DepartmentBoerhinger Ingelheim, Ridgefield, Connecticut; Department of Protein Chemistry and Structural Biology
Genentech Inc.
South San Francisco, CA, USA

Kurt Schroeder
Departments of Biomolecular Engineering and Proteomics & Biological Resources
Genentech Inc.
South San Francisco, CA, USA

Lovejit Singh
Departments of Biomolecular Engineering and Proteomics & Biological Resources
Genentech Inc.
South San Francisco, CA, USA

Nestor Solis
Center for Blood Research
University of British Columbia
Vancouver, British Columbia, Canada

Justin B. Sperry
Department of Analytical Research and Development
Pfizer
Cambridge, MA, USA

Christoph Spiess
Department of Antibody Engineering
Genentech Research and Early Development
South San Francisco, CA, USA

Martin Vanderlaan
Department of Analytical Operations
Genentech Inc.
South San Francisco, CA, USA